Ayan Das, Aniruddha Roy and Nirmal Paul, Global Institute of Management & Technology, India

Complexes of metal ions with organic ligands play an important role in many fields of our life. These metal complexes are widely used in medical diagnosis and therapeutic analysis. These complexes are very familiar with radioisotopes exerting precise chemical and physical properties. Generally, chromium is considered as toxic and essential element depending on its oxidation state in the biological system. Here the dynamic dissociation constants of the complex of Chromium (III) with excellent biocompatible polymer PVP (poly-N-vinylpyrolidone) have been determined. The dissociation constants will give us the idea about the stability of the said complexes. As PVP is a good ligand with different metals within a wide range of pH. Ingestion techniques of radioisotopes to the biological systems may be nicely polished with the knowledge of this kinetic study with chromium. Green methods have been carried out during the whole period of the experiments to maintain the environmental friendly aspects.

HPGe detector, PVP (Poly-N-vinylpyrrolidone), radiotracer, pH, dialysis sac, radionuclide, (n, Υ) reaction, multichannel analyser, chromium (III).