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Computational Methods for Functional Analysis of Gene Expression

Authors

Houda Fyad, Fatiha Barigou and Karim Bouamrane, University of Oran 1 Ahmed Ben Bella, Algeria

Abstract

Sequencing projects arising from high throughput technologies including those of sequencing DNA microarrays allowed to simultaneously measure the expression levels of millions of genes of a biological sample as well as annotate and identify the role (function) of those genes. Consequently, to better manage and organize this significant amount of information, bioinformatics approaches have been developed. These approaches provide a representation and a more 'relevant' integration of data in order to test and validate the hypothesis of researchers throughout the experimental cycle. In this context, this article describes and discusses some of techniques used for the functional analysis of gene expression data.

Keywords

Microarray, genes, genome annotation, functional analysis, expression data, datamining, clustering, classification, Gene ontology.

Full Text  Volume 6, Number 14